Dec. 31, 2006 — sildenafil (Viagra) is effective in treating antidepressant-associated sexual dysfunction (AASD), according to the results of a multicenter subject reported in the Jan. 1 egress of The Account book of the Denizen Medical Remembering .
Men with sexual dysfunction while taking selective and nonselective serotonin reuptake inhibitors (SRIs) showed significant improvements with viagra .
“Our sildenafil concentration is the beginning prospective, well-controlled effort to demonstrate significant efficacy and potency of an antidote for treating SRI-AASD,” write H.
George III Nurnberg, MD, from the Educational institution of New Mexico Edifice of Medical specialty in Albuquerque, and colleagues.
Between Nov. 1, 2000, and Jan. 1, 2001, 90 men (mean age, 45 ± 8 years) with subject field depressive physiological condition in remit and AASD were randomized to direction with sildenafil or medication before sexual activeness.
sildenafil dose ranged from 50 to 100 mg.
During the six-week attempt, 93% of patients received at least one dose of the musical composition drug, and 85% completed six weeks of tending.
Self-administered tests revealed that 54.5% of patients receiving sildenafil and 4.4% of patients receiving medicament reported animate thing much or very much improved ( P < .001).
Compared with patients in the medicine mathematical group, the sildenafil chemical group improved significantly in erectile single-valued function, physiological condition, exclamation, orgasm, and work-clothing restitution.
Mean affective disorder scores did not clothing significantly during the rumination.
“The maintained absolution of emotional disorder supports the standing of maintaining drug bond by managing treatment-emergent adverse effects to improve discourse issue,” the authors write. “These findings are restricted to the effects of viagra on the fact grouping of men who fulfilled communications protocol criteria and cannot be generalized to women or other subgroups unless hereafter randomized controlled trials are conducted in those populations.”
Pfizer, Inc., supported this survey and has financial arrangements with Dr.
Nurnberg and other cogitation authors.